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Nicholas H Carbonetti Selected Research

Pertussis Toxin

1/2022Pertussis Toxin Promotes Pulmonary Hypertension in an Infant Mouse Model of Bordetella pertussis Infection.
1/2021Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo.
11/2017Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the Airways.
1/2017Reduction of Pertussis Inflammatory Pathology by Therapeutic Treatment With Sphingosine-1-Phosphate Receptor Ligands by a Pertussis Toxin-Insensitive Mechanism.
10/2016Pertussis leukocytosis: mechanisms, clinical relevance and treatment.
11/2015Contribution of pertussis toxin to the pathogenesis of pertussis disease.
12/2012Pertussis toxin exacerbates and prolongs airway inflammatory responses during Bordetella pertussis infection.
4/2011Bordetella pertussis infection exacerbates influenza virus infection through pertussis toxin-mediated suppression of innate immunity.
3/2010Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools.
9/2009Pertussis toxin stimulates IL-17 production in response to Bordetella pertussis infection in mice.
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Nicholas H Carbonetti Research Topics

Disease

21Whooping Cough (Pertussis)
01/2022 - 06/2004
19Infections
01/2022 - 11/2003
3Respiratory Tract Infections (Respiratory Tract Infection)
11/2008 - 06/2004
2Cough
01/2021 - 06/2007
2Leukocytosis (Pleocytosis)
01/2021 - 10/2016
2Pneumonia (Pneumonitis)
01/2020 - 01/2019
2Communicable Diseases (Infectious Diseases)
01/2017 - 06/2015
1Pulmonary Hypertension
01/2022
1Inflammation (Inflammations)
01/2021
1Splenomegaly
01/2016
1Asthma (Bronchial Asthma)
10/2014
1Bacterial Infections (Bacterial Infection)
04/2007
1Coinfection
05/2005
1Pulmonary Fibrosis (Fibrosing Alveolitis)
12/2003

Drug/Important Bio-Agent (IBA)

17Pertussis ToxinIBA
01/2022 - 11/2003
12Virulence Factors (Pathogenicity Factors)IBA
01/2019 - 11/2003
5Proteins (Proteins, Gene)FDA Link
10/2016 - 12/2003
5Adenylate Cyclase ToxinIBA
01/2016 - 06/2004
4Sphingosine-1-Phosphate ReceptorsIBA
01/2021 - 06/2015
4VaccinesIBA
12/2020 - 11/2015
3ChemokinesIBA
01/2021 - 11/2008
3Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 01/2016
3ExotoxinsIBA
05/2005 - 11/2003
2LigandsIBA
01/2021 - 01/2017
2CytokinesIBA
01/2021 - 01/2020
2AntigensIBA
01/2016 - 06/2004
2Hemagglutinins (Hemagglutinin)IBA
01/2016 - 06/2004
1EnzymesIBA
01/2021
1Cyclophilins (Cyclophilin)IBA
01/2021
1Toll-Like Receptor 9IBA
01/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021
1Interferon LambdaIBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2020
1Peptidoglycan (Murein)IBA
01/2019
1Cytotoxins (Cytolysins)IBA
01/2019
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2017
1Arachidonic Acid (Vitamin F)IBA
01/2016
1Prostaglandin-E SynthasesIBA
01/2016
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2016
1Dinoprostone (PGE2)FDA Link
01/2016
1EicosanoidsIBA
01/2016
1Interleukin-18 (Interleukin 18)IBA
01/2016
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2016
1Phospholipases A2 (Phospholipase A2)IBA
01/2016
1ChloridesIBA
10/2014
1Carbonic Anhydrase InhibitorsIBA
10/2014
1Acetazolamide (Diamox)FDA LinkGeneric
10/2014
1AnionsIBA
10/2014
1thiocyanateIBA
10/2014
1Bicarbonates (Hydrogen Carbonate)IBA
10/2014
1Interleukin-6 (Interleukin 6)IBA
04/2011
1Interleukin-12 (IL 12)IBA
04/2011
1Interleukin-17 (Interleukin 17)IBA
09/2009
1Clodronic Acid (Clodronate)IBA
04/2007
1Adenosine Diphosphate (ADP)IBA
04/2007
1GTP-Binding Proteins (G-Protein)IBA
04/2007
1Liposomes (Liposome)IBA
04/2007
1CollagenIBA
12/2003
1Messenger RNA (mRNA)IBA
12/2003
1Chemokine CCL18IBA
12/2003

Therapy/Procedure

5Therapeutics
01/2021 - 06/2015
2Intranasal Administration
04/2007 - 05/2005
1Immunomodulation
06/2007